ALS Trajectory Predictor v4 — Clinician Inspection Dashboard

Synthetic cohort · Infinity-style monitoring · latent respiratory trajectory · event prediction

Research demonstrator only. All patients and event probabilities are synthetic. Coefficients are not clinically validated and outputs must not be used for diagnosis or treatment decisions.
ALSFRS-R total
SVC % predicted
Estimated respiratory burden
Support state
Respiratory event risk
within 30 days
Respiratory event risk
within 60 days
Respiratory event risk
within 90 days

Respiratory trajectory and model estimate

Solid line: model estimate. Dashed line: known hidden truth (available only because this is synthetic).
Posterior estimateHidden truthRespiratory event

Current interpretation

Phenotype
Patient drift
Nocturnal SpO₂ P10
Daily steps
Known event

Latent respiratory trajectory with uncertainty

Posterior mean ± approximately 95% posterior interval, compared with hidden synthetic truth. The vertical cursor is the selected analysis date.

ALSFRS-R trajectory

SVC trajectory

Infinity physiological monitoring

Daily summaries generated from the hourly synthetic watch stream. Values to the right of the analysis date are shown as future ground truth only when the cursor advances.
Heart rate
daily median bpm
SpO₂
daily median / nocturnal P10
Temperature
daily median °C
BP trend
synthetic systolic trend

Daily Infinity data around selected date

DateHRSpO₂Noct. P10≤92% frac.TempBP trendStepsNIV

Clinical assessment record

Complete synthetic clinical record. Rows after the selected analysis date are muted as future information.
DateDayALSFRS-RRespiratorySVC %NIVPowered chairSpeech support

Prediction audit at selected date

Posterior mean
Posterior SD
Patient drift/day
True respiratory state
Absolute state error
ALSFRS-R total
Respiratory subscore
SVC
NIV state

Why the risk changed

This is an explanatory decomposition of the transparent synthetic model, not a validated causal attribution.

Full daily model audit trail

DatePosteriorSDTrue resp.Drift/dayRisk 30dRisk 60dRisk 90dALSFRS-RSVCNIV
Clinical concept, model and design: Michael Tremblay.
Intellectual property owner: Cassis Ltd. Copyright © 2026 Cassis Ltd. All rights reserved.